Changes in version 4.1 (2025-09-08)                   

    o   remove depencency on kinship2, replace with bioconductor
	Pedixplorer

    o   index rows of ped/geno by famid_id to match kinship dimnames,
	which makes robust to lc_collate char-sorting settings

                         Changes in version 3.7                         

    o   rename format.relation as format_relation

                  Changes in version 3.3 (2020-02-19)                   

    o   Allow either ped or famid as the pedigree id in ped and geno
	datasets

    o   Allow special relationships for family members, as in kinship2
	package

                  Changes in version 2.9 (2015-10-10)                   

    o   Use trait.adjusted as mean of trait for those with genotype
	data

                         Changes in version 2.6                         

    o   Make sure character ids stay as character ids

    o   Bug fix for no relateds

    o   For X chrom, add check for monomorphic to include within males
	and females only

                  Changes in version 1.4 (2014-03-20)                   

    o   Add argument acc.davies for pedgene. Some kernel tests gave NA
	p-values with default daves accuracy of 1e-6. Performs well
	with default of 1e-5, but give option to user in case NAs
	occur.

    o   return n-variants for the gene tests, now a column in the
	returned object from pedgene

    o   Allow the method to complete if any gene has no markers even
	after all are removed for having zero variance (same genotype)

    o   When a gene has only one marker, the kernel test reduces to
	burden test. Return same test stat and p-value for both. Thanks
	to Seth Ament.

    o   Fix bug where failed to subset genotype matrix when either NA
	in trait or all NA genotypes for a given person, after matching
	geno and ped subject by ped-person ids. Thanks again to Seth
	Ament.

    o   Change maintainer to Jason, rather than Dan.

    o   Add n.noninform to pedgene object, the number of
	non-informative markers that were removed

                         Changes in version 1.0                         

    o   Require ped and person ID columns in genotype data. To match to
	more-complete subjects in pedigree data by ped and person ID.

    o   Added argument checkpeds, allows user to turn off the step that
	performs pedigree checks.

    o   Kinship function (from kinship2) is now called without making a
	pedigree object first. This step allows disconnected pedigrees,
	and identifiers can be either numberic or character.

    o   Perform Davies' p-value for Kernel statistic.

    o   Added package vignette, a simple manual

                         Changes in version 0.5                         

    o   wrapper called pedgene to call pedgene.stats on one gene at a
	time while re-using kinship matrix for all pedigrees

    o   require ped and geno data.frames to have same number of rows

    o   add test script: test.pedgene.R

    o   if map given (with chrom and gene columns), require map to have
	as many rows as geno has columns

    o   define S3 pedgene object, with simple print and plot methods

                         Changes in version 0.1                         

    o   Original release, mostly code from Dan's scripts

    o   pedgene.init pre-calculates some stats, passed to pedgene.stats
	for one single gene